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New Challenges to Health

New Challenges to Health

New Challenges to Health

The Threat of Virus Infection
G. L. Smith, Imperial College of Science, Technology and Medicine, London
W. L. Irving, University of Nottingham
J. W. McCauley, Institute for Animal Health, Compton, Berkshire
D. J. Rowlands, University of Leeds
April 2001
Temporarily unavailable - available from TBC
Hardback
9780521806145

    Viruses continually evolve and adapt, posing new threats to health. This book discusses the ecology of viruses with particular emphasis on the emergence of devastating haemorrhagic disease, and reviews the molecular and cell biological basis of the pathogenesis of several virus diseases. An introduction is given to the mathematical analysis of recurrent epidemic virus disease, such as measles. Neurological and psychological disease is discussed in relation to the pathological mechanisms that may underlie prion disease (such as new variant CJD) and to the possible virus involvement in human psychiatric illness. Virus infections that have come to prominence recently (HIV, bunyaviruses, morbilliviruses and caliciviruses) or that remain a threat (influenza and hepatitis viruses) are discussed. There are also chapters on new and potential niches for virus infections in the immunocompromised, and the problem of the emergence of antiviral drug resistance in viruses for which therapies exist.

    • Emerging and re-emerging infection
    • Virus and prion diseases
    • Epidemiology of virus infection

    Reviews & endorsements

    "I wish every politician, ideologue, and guru in the world would read this book because the likeliest catastrophes in humanity's immediate future are not political, ideological, or religious, but viral...The articles are not sensationalistic...but calm and deeply informed. They are excellent sources for experts...This is an informed and dispassionate study...It is an excellent brief for those who worry more about public health than ICBMs." Quarterly Review of Biology

    See more reviews

    Product details

    April 2001
    Hardback
    9780521806145
    360 pages
    236 × 161 × 28 mm
    0.78kg
    53 b/w illus. 8 colour illus. 23 tables
    Temporarily unavailable - available from TBC

    Table of Contents

    • Preface
    • 1. The viruses in our past, the viruses in our future C. J. Peters
    • 2. Dynamics and epidemiological impact of microparasites B. T. Grenfell
    • 3. The continuing threat of bunyaviruses and hantaviruses R. M. Elliott
    • 4. Calicivirus, myxoma virus and the wild rabbit in Australia: a tale of three invasions B. J. Richardson
    • 5. Potential of influenza A viruses to cause pandemics A. J. Hay
    • 6. The hepatitis viruses as emerging agents of infectious diseases S. M. Lemon
    • 7. The emergence of human immunodeficiency viruses and AIDS R. A. Weiss and H. A. Weiss
    • 8. Morbilliviruses: dangers old and new T. Barrett
    • 9. Structure-function analysis of prion protein C. Weissmann, D. Shmerling, D. Rossi, A. Cozzio, I. Hegyi, M. Fischer, R. Leimeroth and E. Flechsig
    • 10. Endogenous retroviruses and xenotransplantation J. P. Stoye
    • 11. Gammaherpesviral infections and neoplasia in immunocompromised populations C. Boshoff
    • 12. Structure and function of the proteins of Marburg and Ebola viruses H.-D. Klenk, H. Feldmann, V. E. Volchkov, V. A. Volchkova and W. Weissenhorn
    • 13. Epidemic dengue/dengue haemorrhagic fever as a public health problem 1st century D. J. Gubler
    • 14. Borna disease virus - a threat for human mental health? L. Bode and H. Ludwig
    • 15. Antiviral drug development and the impact of drug resistance G. Darby
    • Index.
      Contributors
    • C. J. Peters, B. T. Grenfell, R. M. Elliott, B. J. Richardson, A. J. Hay, S. M. Lemon, R. A. Weiss, H. A. Weiss, T. Barrett, C. Weissmann, D. Shmerling, D. Rossi, A. Cozzio, I. Hegyi, M. Fischer, R. Leimeroth, E. Flechsig, J. P. Stoye, C. Boshoff, H.-D. Klenk, H. Feldmann, V. E. Volchkov, V. A. Volchkova, W. Weissenhorn, D. J. Gubler, L. Bode, H. Ludwig, G. Darby

    • Editors
    • G. L. Smith , Imperial College of Science, Technology and Medicine, London

      Geoffrey Smith is a Wellcome Trust Principal Research Fellow at the Wright-Fleming Institute, Imperial College of Science, Technology and Medicine, UK.

    • W. L. Irving , University of Nottingham

      Will Irving is a Reader in Virology in the Department of Microbiology at the University of Nottingham, UK.

    • J. W. McCauley , Institute for Animal Health, Compton, Berkshire

      John McCauley is a researcher in the Division of Molecular Biology at the Institute of Animal Health, Compton. UK.

    • D. J. Rowlands , University of Leeds

      Dave Rowlands is Professor of Molecular Virology in the Division of Microbiology at the University of Leeds, UK.