Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis
Charles Krieger, University of British Columbia, Vancouver
Amyotrophic lateral sclerosis (ALS), otherwise known as Lou Gehrig's or motor neuron disease, is one of several degenerative diseases of the ageing nervous system. Commonly affecting those in their mid-50s and beyond, it is a progressive illness resulting in death within a few years. This text neatly synthesizes the recent explosion of research into this particular condition to construct a detailed and comprehensive overview. From its epidemiology, molecular biology and pathophysiology right through to clinical assessment and care, Professor Eisen and Dr Krieger use their research expertise and extensive clinical experience to provide this practical and thought-provoking account.
- Comprehensive, timely and well-illustrated overview
- Co-authorship provides balanced, flowing and thought-provoking text
- Authored by internationally renowned experts in the field
Reviews & endorsements
'… this volumes strengths - its clarity, brevity, and breadth of vision - are to be applauded. Where else would one find tidy one-paragraph descriptions of the basis of magnetic resonance spectroscopy, or the difference between an odds ratio and a relative risk? I have already lent out my copy of this handy little one volume summation and recommend it as a launchpad for readers' further investigations into ALS/MND.' Matthew Parton, Journal of Neurology, Neurosurgery and Psychiatry
'This excellent review of ASL is well-written in a language easily understood even by medical students and residents. Thus it appeals to health professionals involved in the care of patients with the disease and makes it different from other books written on this subject.' Cristina Y. Go, Doody's Journal
'The background of the authors ensures that issues relevant to neurologists interested in amyotrophic lateral sclerosis are discussed in a comprehensive and practical way. Readers will be impressed as well as educated by the data gathered from the author's experience over a period of almost two decades.' The New England Journal of Medicine
'The volume is amply illustrated and balanced in its approach. It is strongly recommended to all physicians, researchers and health care professionals involved in the management of ALS sufferers and their carers. It will also be a useful reference resource for medical libraries.' Neuromuscular Disorders
Product details
October 1998Hardback
9780521581035
324 pages
236 × 158 × 21 mm
0.65kg
51 b/w illus. 40 tables
Available
Table of Contents
- Foreword
- Preface
- Acknowledgements
- Abbreviations
- 1. Epidemiological considerations
- 2. The clinical spectrum of ALS
- 3. The pathology of ALS
- 4. Pathogenic mechanisms in ALS
- 5. The role of clinical neurophysiology in ALS
- 6. The application of imaging techniques
- 7. ALS therapy, therapeutic trials and neuroprotection
- 8. The overlap syndromes
- References
- Index.
