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Medication-Resistant Epilepsy

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Medication-Resistant Epilepsy

Medication-Resistant Epilepsy

Diagnosis and Treatment
John M. Stern, Geffen School of Medicine at UCLA, Los Angeles, CA
Raman Sankar, Geffen School of Medicine at UCLA, Los Angeles, CA
Michael Sperling, Jefferson Hospital for Neurosciences, Philadelphia, PA
October 2020
Available
Hardback
9781107139886
$123.00
USD
Hardback
USD
eBook
    Description

    Fifty million people worldwide have epilepsy and yet up to 35% of patients experience seizures that are resistant to anti-epileptic drugs. Patients with medication-resistant epilepsy have increased risks of premature death, psychosocial dysfunction and a reduced quality of life. This key resource delivers guidance for all clinicians involved in caring for patients with medication-resistant epilepsy in order to reduce these risks. Covering the epidemiology, biology, causes and potential treatments for medication-resistant epilepsy, this definitive and focused text reviews the clinical care needs of patients. Guidance is practical and includes treatment for specialized groups including pediatric patients and those with psychiatric comorbidities. Several promising non-pharmacologic interventions available for patients, such as surgery, neuromodulation diet therapy and botanical treatment are explored in detail. Leading international figures from a range of disciplines bring their expertise together holistically in this essential manual.

    • Focuses on the clinical care needs of patients, making it an essential guide for practicing clinicians
    • A broad yet detailed scope allows for the entire text to be read, bringing together topics holistically in an accessible handbook format
    • Treatments covered are cutting-edge, with the latest research and evidence discussed in detail meaning clinicians will be able to make fully informed decisions for their patients' care

    Reviews & endorsements

    ‘This is a wonderful textbook that systematically covers a complex and challenging subset of epilepsy patients. The novelty lies in the fact that there are few textbooks that offer such a comprehensive review - medication resistant epilepsy is often relegated to a single chapter in other comparable textbooks in epilepsy. The book excels in introducing the topic of medication resistant epilepsy (including a functional definition) and offering a detailed review of treatments available.’ Mahnoor Rehman, Doody's Book Review Service

    See more reviews

    Product details

    October 2020
    Hardback
    9781107139886
    286 pages
    253 × 194 × 17 mm
    0.77kg
    80 b/w illus. 35 tables
    Available

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    This title is available for institutional purchase via Cambridge Core

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    Contents

    Table of Contents

    • 1. The natural history of epilspy Byugin Lee and Sung-Eun Kim
    • 2. Challenges in identifying medication-resistant epilepsy Martin J. Brodie and Pauls Auce
    • 3. International league against epilepsy's definition in medication-resistant epilepsy Colin B. Josephson and Samuel Wiebe
    • 4. The economic impact of medication-resistant epilepsy Charles E. Begley and Shin Jeong
    • 5. Social consequences of medication-resistant epilepsy Amy Crepeau and Joesph I. Sirven
    • 6. Morality and morbidity of medication-resistant epilepsy Nuria Lacuey and Samden D. Lhatoo
    • 7. Models for medication-resistant epilepsy Raman Sankar
    • 8. Neurobiology of medication-resistant epilepsy Jerome Engel Jr
    • 9. Genetic causes of medication-resistant epilepsy Thomas N. Ferraro, Bradford D. Fischer and Russel J. Buono
    • 10. Malformation of cortical development as causes of medication-resistant epilepsy Ruben Kuzniecky
    • 11. Hippocampal sclerosis as a cause of medication-resistant epilepsy Fahmida Amin Chowdhury, Beate Diehl and Maria Thom
    • 12. Autoimmune causes of medication-resistant epilepsy Anteneh M. Feyissa and Jeffrey W. Britton
    • 13. Medication-resistant epilepsy syndromes in children Elia M. Pestana Knight and Elaine Wyllie
    • 14. Medication-resistant epilepsy in adults Martin Holtkamp and Felix Benninger
    • 15. Approach to the treatment of medication-resistant epilepsy John Stern
    • 16. Pharmacotherapy for medication-resistant epilepsy Graham A. Powell and Anththony G. Marson
    • 17. Reproductive health for women with medication-resistant epilepsy Jiyeon Yoo and Cynthia Harden
    • 18. Resective medication-resistant epilepsy surgery Barbara C. Jobst and Krzyszof A. Bujarski
    • 19. Ablative surgery for medication-resistant epilepsy Christian Hoelscher, Kofi-Buaku Atsina, Chengyuan Wu and Ashwini Sharan
    • 20.1. Vagus and trigeminal nerve stimulation treatment of medication-resistant epilepsy George Nune and Christianne Heck
    • 20.2. Electrical stimulation of the anterior nucleus of the thalamus for medication-resistant epilepsy Mohamed Z. Koubeissi and Amr Ewida
    • 20.3. Responsive neurostimulation of the brain for medication-resistant epilepsy Ritu Kapur and Martha J. Morrell
    • 20.4. Stimulation treatments for medication-resistant epilepsy: transcranial magnetic stimulation Lara M. Schrader
    • 21. Diet therapy for medication-resistant epilepsy Eric H. Kossoff and Daniel B. Lowenstein
    • 22. Botanical treatments for medication-resistant epilepsy Steven C. Schachter
    • 23. Psychiatric comorbidities in medication-resistant epilepsy Andres M. Kanner.
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    About the authors
      Contributors

    • Byugin Lee, Sung-Eun Kim, Martin J. Brodie, Pauls Auce, Colin B. Josephson, Samuel Wiebe, Charles E. Begley, Shin Jeong, Amy Crepeau, Joesph I. Sirven, Nuria Lacuey, Samden D. Lhatoo, Raman Sankar, Jerome Engel Jr,Thomas N. Ferraro, Bradford D. Fischer, Russel J. Buono, Ruben Kuzniecky, Fahmida Amin Chowdhury, Beate Diehl, Maria Thom, Anteneh M. Feyissa, Jeffrey W. Britton, Elia M. Pestana Knight, Elaine Wyllie, Martin Holtkamp, Felix Benninger, John Stern, Graham A. Powell, Anththony G. Marson, Jiyeon Yoo, Cynthia Harden, Barbara C. Jobst, Krzyszof A. Bujarski, Christian Hoelscher, Kofi-Buaku Atsina, Chengyuan Wu, Ashwini Sharan, George Nune, Christianne Heck, Mohamed Z. Koubeissi, Amr Ewida, Ritu Kapur, Martha J. Morrell, Lara M. Schrader, Eric H. Kossoff, Daniel B. Lowenstein, Steven C. Schachter, Andres M. Kanner

      • Editors
    • John M. Stern , Geffen School of Medicine at UCLA, Los Angeles, CA

      John Stern is a Professor and Director of the Epilepsy Clinical Program in the Department of Neurology at the Geffen School of Medicine, University of California, Los Angeles.

    • Raman Sankar , Geffen School of Medicine at UCLA, Los Angeles, CA

      Raman Sankar is Chief of Pediatric Neurology and Distinguished Professor in the Departments of Neurology and Paediatrics at the Geffen School of Medicine, University of California, Los Angeles.

    • Michael Sperling , Jefferson Hospital for Neurosciences, Philadelphia, PA

      Michael Sperling is the Director of Jefferson Comprehensive Epilepsy Center, Philadelphia, and Professor of Neurology at Thomas Jefferson University, Philadelphia.

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