Ion Channels
Ion Channels
$94.00
USDIon channels are crucial components of living cells. Situated in the cell membrane, they allow ions to pass from one side of the membrane to the other. This book provides an overview of ion channel study, including up-to-date coverage of the permeability and selectivity of channels, their gating and modulation, their response to drugs and toxins, and the human diseases that result from channel malfunction. Students of molecular biology, biochemistry, physiology, and neurobiology will benefit from this modern, concise text.
- Up-to-date introduction aimed at students. It does not assume much initial knowledge but takes the reader to the frontiers of understanding
- Has a molecular emphasis, based on recent advances in gene therapy and electrophysiology
- Covers the diseases caused when channels don't work properly (such as cystic fibrosis)
Reviews & endorsements
"...[a] clear and concise introduction to the physics, chemistry, and molecular biology used for ion channel research...what distinguishes this book from standard textbooks is the inclusion of some details of the experimental design, so as to allow the reader to have a better feel of how the studies were done and how the abstract theories emerged from the data...The authors have done a fantastic job in presenting a balanced view and in pointing out unsettled areas." Lily Yeh Jan, Cell
"...this book takes the reader to the frontiers of current research and should be of considerable interest to reproductive and developmental biologists." Ralph B.L. Gwatkin, Molecular Reproduction and Development
"The new Ion Channels book by David J. Aidley and Peter R. Stanfield offers an easy and smooth initiation....The authors have done a fantastic job in presenting a balanced view and in pointing out unsettled areas." Lily Yeh Jan, Cell
Product details
August 1996Paperback
9780521498821
320 pages
246 × 189 × 17 mm
0.573kg
132 b/w illus. 20 tables
Available
Table of Contents
- Preface
- 1. Introduction
- 2. Ions on the move
- 3. Investigating channel activity
- 4. Molecular structures
- 5. Permeability and selectivity
- 6. Gating and modulation
- 7. Drugs and toxins
- 8. Dysfunctional channels in human disease
- 9. Not the last word
- References
- Index.
