Our systems are now restored following recent technical disruption, and we’re working hard to catch up on publishing. We apologise for the inconvenience caused. Find out more

Recommended product

Popular links

Popular links


Biosimulation

Biosimulation

Biosimulation

Simulation of Living Systems
Daniel A. Beard, Medical College of Wisconsin
April 2012
Available
Hardback
9780521768238
AUD$193.59
exc GST
Hardback
USD
eBook

    This practical guide to biosimulation provides the hands-on experience needed to devise, design and analyze simulations of biophysical processes for applications in biological and biomedical sciences. Through real-world case studies and worked examples, students will develop and apply basic operations through to advanced concepts, covering a wide range of biophysical topics including chemical kinetics and thermodynamics, transport phenomena, and cellular electrophysiology. Each chapter is built around case studies in a given application area, with simulations of real biological systems developed to analyze and interpret data. Open-ended project-based exercises are provided at the end of each chapter, and with all data and computer codes available online (www.cambridge.org/biosim) students can quickly and easily run, manipulate, explore and expand on the examples inside. This hands-on guide is ideal for use on senior undergraduate/graduate courses and also as a self-study guide for anyone who needs to develop computational models of biological systems.

    • Provides hands-on experience for devising, designing and analyzing simulations of biophysics processes
    • Develops through real-world case studies and practical worked examples
    • All computer codes for the examples in the book are provided online so students can use the example codes as a starting point to develop their own applications

    Product details

    April 2012
    Hardback
    9780521768238
    320 pages
    252 × 193 × 18 mm
    0.83kg
    115 b/w illus. 19 tables 50 exercises
    Available

    Table of Contents

    • 1. Introduction to simulation of biological systems
    • 2. Transport and reaction of solutes in biological systems
    • 3. Physiologically-based pharmacokinetic modeling
    • 4. Cardiovascular systems simulation
    • 5. Chemical reaction systems: thermodynamics
    • 6. Chemical reaction systems: kinetics
    • 7. Chemical reaction systems: large-scale systems simulation
    • 8. Cellular electrophysiology
    • 9. Appendices: mathematical and computational techniques.
    Resources for
    Type
    Code for Chapter 8
    Size: 95.21 KB
    Type: application/zip
    Code for Chapter 5
    Size: 77.07 KB
    Type: application/zip
    Code for Chapter 3
    Size: 100.52 KB
    Type: application/zip
    Code for Chapter 4
    Size: 75.33 KB
    Type: application/zip
    Code for Chapter 2
    Size: 145.42 KB
    Type: application/zip
    Code for Chapter 1
    Size: 54.25 KB
    Type: application/zip
      Author
    • Daniel A. Beard , Medical College of Wisconsin

      Daniel A. Beard is a Professor in the Biotechnology and Bioengineering Center and the Department of Physiology at the Medical College of Wisconsin. Research in his laboratory is focused on systems engineering approaches to understanding the operation of physiological systems in health and disease. A recent major effort in his group has been on theoretical and experimental characterization of the thermodynamics, kinetics and electrophysiology of cardiac mitochondria. Additional research interests include non-equilibrium thermodynamics in biochemical networks, mass transport and microvascular exchange in physiological systems, and drug metabolism and physiologically-based pharmacokinetics.