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Multiple Sclerosis

All titles
Multiple Sclerosis

Multiple Sclerosis

Recovery of Function and Neurorehabilitation
Jürg Kesselring, Rehabilitation Centre, Valens, Switzerland
Giancarlo Comi, Istituto Scientifico H. San Raffaele, Milan
Alan J. Thompson, University College London
October 2010
Available
Hardback
9780521888325
NZD$182.95
inc GST
Hardback
USD
eBook
    Description

    Recent developments in basic and applied science have led to better understanding of disease mechanisms and more efficient therapies for multiple sclerosis. The most effective way of managing these patients is through a carefully planned neurorehabilitation programme. The main aims are to reduce disability and handicap and improve functions through effective training, stimulating activity and social participation. As the first text on recovery of function and neurorehabilitation in MS, this book focuses on mechanisms of recovery, application of neuroplasticity to therapeutic interventions, and determination of the efficiency of these interventions. Basic principles of neurorehabilitation in MS are described, as well as techniques for treating specific syndromes which may occur in MS. Written and edited by leading clinicians and researchers, the book achieves an excellent balance between basic science, pathophysiology, and clinical rehabilitation. An essential resource for clinicians and therapists treating patients with multiple sclerosis, neurophysiologists, and health care advisors.

    • Up-to-date overview of mechanisms of functional recovery and neurorehabilitation in MS, explaining the application of neuroplasticity
    • Explains the application of basic science to inflammation and demyelination in the central nervous system
    • Written by world experts in the field, providing an authoritative and comprehensive resource

    Product details

    October 2010
    Hardback
    9780521888325
    260 pages
    257 × 193 × 16 mm
    0.75kg
    36 b/w illus. 18 colour illus. 10 tables
    Available

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    This title is available for institutional purchase via Cambridge Core

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    Contents

    Table of Contents

    • Preface
    • Part I. Basic Mechanisms:
    • 1. Conduction studies in multiple sclerosis Kai M. Rösler and Christian W. Hess
    • 2. The physiopathology of multiple sclerosis Giancarlo Comi
    • 3. Synaptic changes in multiple sclerosis. Do they occur? How effectively can they be analyzed? Vincenzo Zimarino, Maddalena Ripamonti, Marcello Belfiore, Mattia Ferro and Antonio Malgaroli
    • 4. Sodium channel expression and function in multiple sclerosis Lakshmi Bangalore, Joel A. Black, Michael D. Carrithers and Stephen G. Waxman
    • 5. Basic mechanisms of functional recovery Björn Zörner and Martin E. Schwab
    • 6. The adult human oligodendrocyte precursor cell: a key player in myelin repair Julia M. Rist and Robin J. M. Franklin
    • 7. Tissue regeneration and repair in multiple sclerosis: the role of neural stem cells Stefano Pluchino, Roberto Furlan, Luca Muzio and Gianvito Martino
    • 8. Schwann cells as a potential cell-based therapy for multiple sclerosis Violetta Zujovic and Anne Baron-Van Evercooren
    • Part II. Assessment of Mechanisms and Disease Status:
    • 9. MRI to study white matter damage in multiple sclerosis Marco Rovaris, Annalisa Pulizzi and Massimo Filippi
    • 10. MRI to assess gray matter damage in multiple sclerosis Massimo Filippi, Federica Agosta and Maria A. Rocca
    • 11. Application of fMRI in multiple sclerosis Massimo Filippi and Maria A. Rocca
    • 12. fMRI in focal CNS damage Patrizia Pantano and Eytan Raz
    • 13. Electrophysiological assessment in multiple sclerosis Letizia Leocani and Giancarlo Comi
    • 14. fMRI monitoring of therapeutic interventions in multiple sclerosis Massimo Filippi and Maria A. Rocca
    • Part III. Rehabilitation - General Aspects:
    • 15. How to measure the effects of rehabilitation Stefan J. Cano and Alan J. Thompson
    • 16. Value and limits of rehabilitation in multiple sclerosis Serafin Beer
    • 17. Prognosis in neurorehabilitation Angelo Ghezzi and Annalisa Rizzo
    • 18. Clinical trials to test rehabilitation Alessandra Solari
    • Part IV. Rehabilitation - Sectorial Interventions:
    • 19. Spasticity in multiple sclerosis Mauro Zaffaroni
    • 20. Cognitive rehabilitation in multiple sclerosis Dawn W. Langdon
    • 21. Disorders of mood and affect in multiple sclerosis Anthony Feinstein and Omar Ghaffar
    • 22. Bladder dysfunction in multiple sclerosis Clare J. Fowler and Gustav Kiss
    • 23. Ataxia and imbalance in multiple sclerosis Luigi Tesio
    • 24. Sexual problems in multiple sclerosis Per Olov Lundberg
    • 25. Bulbar problems in multiple sclerosis Susan L. McGowan, Lucy Rodriguez and Clare Laing
    • 26. Back home Carlo Pozzilli and Emanuela Onesti
    • Index.
      • Show more

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    Additional Information
    About the authors
      Contributors

    • Kai M. Rösler, Christian W. Hess, Giancarlo Comi, Vincenzo Zimarino, Maddalena Ripamonti, Marcello Belfiore, Mattia Ferro, Antonio Malgaroli, Lakshmi Bangalore, Joel A. Black, Michael D. Carrithers, Stephen G. Waxman, Björn Zörner, Martin E. Schwab, Julia M. Rist, Robin J. M. Franklin, Stefano Pluchino, Roberto Furlan, Luca Muzio, Gianvito Martino, Violetta Zujovic, Anne Baron-Van Evercooren, Marco Rovaris, Annalisa Pulizzi, Massimo Filippi, Federica Agosta, Maria A. Rocca, Patrizia Pantano, Eytan Raz, Letizia Leocani, Stefan J. Cano, Alan J. Thompson, Serafin Beer, Angelo Ghezzi, Annalisa Rizzo, Alessandra Solari, Mauro Zaffaroni, Dawn W. Langdon, Anthony Feinstein, Omar Ghaffar, Clare J. Fowler, Gustav Kiss, Luigi Tesio, Per Olov Lundberg, Susan L. McGowan, Lucy Rodriguez, Clare Laing, Carlo Pozzilli, Emanuela Onesti

      • Editors
    • Jürg Kesselring , Rehabilitation Centre, Valens, Switzerland

      Jürg Kesselring is Head of the Department of Neurology and Neurorehabilitation, Rehabilitation Centre, Valens, Switzerland.

    • Giancarlo Comi , Istituto Scientifico H. San Raffaele, Milan

      Giancarlo Comi is Professor of Neurology, Chairman of the Department of Neurology, and Director of the Institute of Experimental Neurology, Vita-Salute San Raffaele University, Scientific Institute San Raffaele, Milan, Italy.

    • Alan J. Thompson , University College London

      Alan J. Thompson is Vice-Dean and Deputy Head of the Faculty of Biomedical Sciences at University College London, Director of the UCL Institute of Neurology, Programme Director for the Neurological Disorders theme of UCL Partners (Academic Health Science Centre), and Deputy Director of the Comprehensive Biomedical Research Centre. He is the Garfield Weston Professor of Clinical Neurology and Neurorehabilitation, and is head of the Neurorehabilitation research group in the Institute of Neurology's Department of Brain Repair and Rehabilitation, London, UK.

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