Neuromuscular Disease

There are over 800 neuromuscular disorders and this can leave clinicians feeling lost as they try to diagnose and manage patients. On the basis of 66 adult and paediatric neuromuscular case vignettes, readers will be walked through using case histories and clinical manifestations as a starting point for diagnosis. For each case, diagnostic tools, disease pathogenesis, prognosis and treatment options are discussed. Symptoms, signs and syndromes are cross-linked to help the reader navigate the array of disorders. Accompanying tables explain differential diagnoses and 30 videos demonstrate clinical features. This second edition has been thoroughly updated as the neuromuscular subspecialty has developed from clinically and pathologically descriptive to making use of new diagnostic technologies and therapies. Neurologists at all levels, paediatricians, internists, geneticists, rehabilitation physicians, physiotherapists and researchers in the field will find this an invaluable guide, as they seek to familiarise themselves with this complex range of disorders.

• A comprehensive introductory chapter and many tables help to cross-link various symptoms and signs, aiding recognition of phenotypes and diseases
• 30 videos demonstrate the clinical manifestations of diseases, including recordings of EMG, muscle and nerve ultrasound investigations, helping readers assess their patients
• Written by experienced neurologists drawing on years of experience diagnosing and managing these disorders
• Practical chapters on genetic testing, electrodiagnostic investigation, imaging tools, pathology and management help practicing physicians to apply new developments in the fields of molecular genetic testing, treatment and care