Microarray Bioinformatics
DNA microarrays have revolutionized molecular biology and are becoming a standard tool in the field. Dov Stekel's book is a comprehensive guide to the mathematics, statistics, and computing required to use microarrays successfully. Unlike traditional molecular biology, the successful use of DNA microarrays requires the application of statistics and computing to design the arrays and experiments, and to analyze and manage the data. This book is written for researchers, clinicians, and laboratory managers.
- A balanced and comprehensive guide to all microarray bioinformatics, accessible to students from both biology and bioinformatics backgrounds
- Based on the highly successful microarray bioinformatics course at Oxford University and written by the course's director, an experienced instructor
- Detailed glossary of terms provided by the Microarray Gene Expression Data Society, who define the standard terms used in the field internationally
Reviews & endorsements
"...excellent and clearly written...concise and most informative, a pleasure to read. It should be examined by anyone interested in this means of analysis."
ASM News
"The book would be ideal for biologists who wish to gain a grasp of the different analysis techniques available to the microarray user."
Society for General Microbiology
Product details
September 2003Paperback
9780521525879
280 pages
248 × 178 × 17 mm
0.612kg
116 b/w illus. 8 colour illus. 58 tables
Available
Table of Contents
- 1. Microarrays: making them and using them
- 2. Sequence databases for microarrays
- 3. Computer design of oligonucleotide probes
- 4. Image processing
- 5. Normalization
- 6. Measuring and quantifying microarray variability
- 7. Analysis of differentially expressed genes
- 8. Analysis of relationships between genes, tissues or treatments
- 9. Classification of tissues and samples
- 10. Experimental design
- 11. Data storage, standards and sharing
- Appendix A. Glossary.