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Molecular Pathology with Online Resource

Molecular Pathology with Online Resource

Molecular Pathology with Online Resource

A Practical Guide for the Surgical Pathologist and Cytopathologist
John M. S. Bartlett, Ontario Institute for Cancer Research, Toronto
Abeer Shaaban, Queen Elizabeth Hospital Birmingham
Fernando Schmitt, University of Porto
February 2016
Print/online bundle
9781107443464
$240.00
USD
Print/online bundle
1 Static online product, 1 Hardback

    This practical manual provides a comprehensive yet concise guide to state-of-the-art molecular techniques and their applications. It starts with an overview of the essential principles of molecular techniques, followed by separate chapters detailing the use of these techniques in particular tissues and organs, and describing recommended treatment plans. Each chapter covers the tests available, their advantages, limitations, and use as diagnostic and prognostic tools, with key learning points at the end of each topic. Using both histologic and cytologic samples, it discusses how to interpret test results in a pathologic context and enables trainees and practicing pathologists to gain an in-depth understanding of molecular diagnostic techniques and how to incorporate them into routine diagnostic practice.

    Aiding the daily practice of refining diagnosis, as well as offering a didactic approach, this book is an essential reference for practicing pathologists and cytopathologists as well as trainees in pathology.

    • Offers a system-specific molecular approach in tissues and cytological preparations and covers current and future trends in molecular pathology to familiarize pathologists and cytopathologists with molecular diagnostic and prognostic criteria
    • Describes the application of molecular techniques in diagnostic histopathology, cytopathology and clinical management
    • Each chapter ends with a set of key learning points, offering a summary as well as a learning tool to surgical pathologists and cytopathologists

    Product details

    February 2016
    Print/online bundle
    9781107443464
    414 pages
    252 × 195 × 25 mm
    1.32kg
    86 colour illus. 38 tables
    Available

    Table of Contents

    • List of contributors
    • Preface
    • 1. An introduction to molecular pathology John M. S. Bartlett
    • 2. Molecular regulation of cellular function Marsela Braunstein and John M. S. Bartlett
    • 3. Practical application of molecular techniques in diagnostic histopathology and cytopathology and clinical management Abeer Shaaban and Fernando Schmitt
    • 4. Fluorescent and non-fluorescent in situ hybridization Jane Bayani and John M. S. Bartlett
    • 5. Clinical applications of the polymerase chain reaction for molecular pathology Angela B. Y. Hui, Annette D. Wong and Carlo V. Hojilla
    • 6. Are microarrays ready for prime time? Jane Bayani and John M. S. Bartlett
    • 7. Tissue microarrays Luigi Tornillo
    • 8. Sequencing Andrew M. K. Brown, Philipe C. Zuzarte and Paul M. Krzyzanowski
    • 9. Microsatellite instability in colorectal cancer Maria Sofia Fernandes, Raquel Seruca and Sérgia Velho
    • 10. Mutational analysis Aaron R. Hansen, Mahadeo A. Sukhai, Hal K. Berman, Suzanne Kamel-Reid and Philippe L. Bedard
    • 11. Tumors of the breast Cathy B. Moelans, Petra van der Groep, Robert Kornegoor, Jelle Wesseling and Paul J. van Diest
    • 12. Tumors of the female genital system Adhemar Longatto Filho, Sigurd F. Lax and Bin Yang
    • 13. Tumours of the male urogenital system Kirsten D. Mertz and Lukas Bubendorf
    • 14. Tumors of the gastrointestinal system Manuel Salto-Tellez, Benedict Yan, Roseann I. Wu and Martha Bishop Pitman
    • 15. Soft tissue, bone and skin tumours Stamatios Theocharis and Jerzy Klijanienko
    • 16. Cardio-thoracic tumors Umberto Malapelle, Claudio Bellevicine, Elena Vigliar and Giancarlo Troncone
    • 17. Tumors of the endocrine system Sylvia L. Asa and Ozgur Mete
    • 18. Haematological malignancies of the lymph nodes Sarah E. Coupland and Pedro Farinha
    • 19. Pediatric tumors Paul Roberts, Susan Picton and Jens Stahlschmidt
    • 20. Serous effusions Ben Davidson
    • 21. Academic applications and future of molecular pathology Manuel Salto-Tellez and Benedict Yan
    • Index.
      Contributors
    • John M. S. Bartlett, Marsela Braunstein, Abeer Shaaban, Fernando Schmitt, Jane Bayani, Angela B. Y. Hui, Annette D. Wong, Carlo V. Hojilla, Luigi Tornillo, Andrew M. K. Brown, Philipe C. Zuzarte, Paul M. Krzyzanowski, Maria Sofia Fernandes, Raquel Seruca, Sérgia Velho, Aaron R. Hansen, Mahadeo A. Sukhai, Hal K. Berman, Suzanne Kamel-Reid, Philippe L. Bedard, Cathy B. Moelans, Petra van der Groep, Robert Kornegoor, Jelle Wesseling, Paul J. van Diest, Adhemar Longatto Filho, Sigurd F. Lax, Bin Yang, Kirsten D. Mertz, Lukas Bubendorf, Manuel Salto-Tellez, Benedict Yan, Roseann I. Wu, Martha Bishop Pitman, Stamatios Theocharis, Jerzy Klijanienko, Umberto Malapelle, Claudio Bellevicine, Elena Vigliar, Giancarlo Troncone, Sylvia L. Asa, Ozgur Mete, Sarah E. Coupland, Pedro Farinha, Paul Roberts, Susan Picton, Jens Stahlschmidt, Ben Davidson

    • Editors
    • John M. S. Bartlett , Ontario Institute for Cancer Research, Toronto

      John M. S. Bartlett, PhD, FRCPath, is Director of Transformative Pathology and Improved Management of Early Cancer at the Ontario Institute for Cancer Research, Toronto, Ontario, Canada.

    • Abeer Shaaban , Queen Elizabeth Hospital Birmingham

      Abeer Shaaban is Consultant Pathologist at the Department of Cellular Pathology, Queen Elizabeth Hospital, Birmingham, UK, and Lecturer at the Department of Pathology, Tanta University Hospital, Tanta, Egypt.

    • Fernando Schmitt , University of Porto

      Fernando Schmitt is Director of the Department of Medicine and Pathology at the Laboratoire National de Sante, Dudelange, Luxembourg.