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Fine-Tuning Life

Fine-Tuning Life

Fine-Tuning Life

A Guide to MicroRNAs, Your Genome's Master Regulators
David C. Henshall, RCSI University of Medicine & Health Sciences, Dublin
June 2024
Available
Paperback
9781009466424
$39.99
USD
Paperback

    Take a journey into the fascinating world of microRNA, the genome's master controllers. Discovered in 1993, our genome's master controllers are critical to the evolution of complex life, including humans. This captivating book tells their story, from their discovery and unique role in regulating protein levels to their practical applications in brain health and other branches of medicine. Written by a neuroscientist, it provides an in-depth look at what we know about microRNAs and how we came to know it. Explore the impact of these molecular conductors on your life and gain a new appreciation for the precision they bring to the molecular noise in our cells. Perfect for students of neuroscience, life sciences such as biochemistry and genetics and the curious public alike, this is the captivating tale of the conductors of life's molecular orchestra.

    • Offers a tangible sense of the job of a researcher, with insights into how the best scientists in the world design experiments and present results
    • Conveys a sense of the joy of the scientific journey and how a field can expand from humble discoveries to global research phenomena
    • Draws the reader in to what is most relevant to our brain and its function in health and disease

    Reviews & endorsements

    ‘This is an outstanding book that clearly explains the discovery, functions, and applications of a biologically complex topic in a manner easily understandable by a wide audience. The author's expert knowledge of the subject matter comes through in this well written book.’ Mark F. Sanders, Doody's Reviews

    See more reviews

    Product details

    June 2024
    Paperback
    9781009466424
    290 pages
    234 × 156 × 15 mm
    0.495kg
    Available

    Table of Contents

    • Introduction A journey with microRNA
    • 1. Discovered! A new regulator of gene activity
    • 2. MicroRNAs emerge as master controllers
    • 3. Epic journey: From biogenesis to extinction
    • 4. Opening act: Fine-tuning during development
    • 5. MicroRNAs shape the machinery of our minds
    • 6. Centre of the electrical storm: MicroRNAs and epilepsy
    • 7. MicroRNAs become medicines
    • 8. Circulating microRNAs provide a diagnosis
    • 9. Finale and encore for microRNAs.
      Author
    • David C. Henshall , RCSI University of Medicine & Health Sciences, Dublin

      David C. Henshall is professor of molecular physiology and neuroscience and Director of the FutureNeuro Research Centre at the RCSI University of Medicine and Health Sciences in Dublin, Ireland. He has published 250 articles and book chapters and is an authority on models, mechanisms and treatment of drug-resistant epilepsy.