Dementia and Normal Aging
Age has been identified as the strongest risk factor for Alzheimer's disease, and is also strongly associated with vascular dementia. With this relationship in mind, this book looks upon the challenge of dementia as establishing its true relationship with normal aging. The traditional disease model of dementia may have obscured important clues about many underlying causes and features of dementia. In this book, experts and pioneers in the fields of aging and dementia make an important contribution to the understanding of dementia by reappraising the latest research in the light of the continuum model. Evidence for and against numerous models of dementia are discussed with particular relevance to the relationship between Alzheimer's and normal aging. Ranging from molecular genetics and fundamental neurobiology to issues of diagnosis and the provision of services, this is a challenging work in its breadth and level of argument, which has far reaching implications for the study of dementia, and indeed of the mind itself. As a review of current thinking and research it will serve as an essential text for clinicians and scientific investigators.
- An essential review by experts of current thinking and research into dementia
- Challenging in breadth and level of argument
- Will stimulate enquiry and debate on a wide range of related issues, including care of the aged cases of dementia
Reviews & endorsements
'In summary, because of its many excellent chapters, updated references and cogent discussions the book should constitute a very informative and instructive reading for psychiatrists, gerontologists and psychologists. It can also be of interest to geneticists and sociologists, and be recommended as a comprehensive reference on aging and dementia to nurses, medical students and general practitioners.' Neuropsychologia
Product details
June 1994Hardback
9780521413930
589 pages
236 × 156 × 39 mm
1.183kg
62 b/w illus. 1 colour illus. 53 tables
Unavailable - out of print
Table of Contents
- List of contributors
- Foreword E. S. Paykel
- Preface F. A. Huppert
- Acknowledgement
- Part I. Introduction:
- 1. What is the relationship between dementia and normal aging? F. A. Huppert and C. Brayne
- Part II. The Development of Contemporary Views of Dementia:
- 2. Dementia and aging since the 19th century G. E. Berrios
- 3. The history of research into dementia and its relationship to current concepts W. A. Lishman
- 4. The relationship between normal aging of the brain and dementia Sir Martin Roth
- Part III. The Diagnosis of Dementia Today:
- 5. International criteria and differential diagnosis A. S. Henderson and N. Sartorius
- 6. Mild dementia: a clinical perspective D. W. O'Connor
- 7. Neurological aspects of dementia and normal aging J. R. Hodges
- 8. Imaging and dementia C. E. L. Freer
- Part IV. Research Methodology and Population Studies:
- 9. How common are cognitive impairment and dementia? An epidemiological viewpoint C. Brayne
- 10. What are the risk factors for dementia? J. A. Mortimer
- 11. How do risk factors for dementia relate to current theories on mechanisms of aging? T. B. L. Kirkwood
- 12. A method for measuring dementia as a continuum in community surveys A. F. Jorm
- Part V. Normal Ageing and Dementia During Life:
- 13. The meaning of dementia to those involved as carers P. A. Pollitt
- 14. Personality and behaviour in dementia and normal aging T. Hope
- 15. Memory function in dementia and normal aging - dimension of dichotomy? F. A. Huppert
- 16. Language function in dementia and normal aging D. Kempler and E. M. Zelinski
- 17. Visuospatial dysfunction in dementia and normal elderly J. V. Filoteo, D. C. Delis, P. J. Massman and N. Butters
- Part VI. Neurobiology of Normal Aging and Dementia:
- 18. Dementia and normal aging: neuropathology M. Esiri
- 19. Cholinergic component of aging and dementia E. K. Perry, J. A. Court, M. A. Piggott and R. H. Perry
- 20. Molecular characterization of the neurologenitive changes which distinguish normal aging from Alzheimer's disease C. Wischik, C. Harrington and E. B. Mukaetova-Ladinska
- 21. Genetic linkage in Alzheimer's disease S.-J. Richards and C. van Broeckhoven
- Part VII. Health Care and Social Policy Issues:
- 22. Health care policy and planning for dementia: an international perspective B. Cooper
- 23. Public health implications of a continuum of dementia K.-T. Khaw
- Index.