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Tumor Immunology

Tumor Immunology

Tumor Immunology

Immunotherapy and Cancer Vaccines
A. G. Dalgleish, St George's Hospital Medical School, University of London
M. J. Browning, University of Leicester
Karol Sikora
November 2010
Available
Paperback
9780521159470
$61.00
USD
Paperback
USD
Hardback

    This 1996 volume reviewed advances in the field of human tumour immunology, particularly in relation to the potential for immune intervention in preventing or treating tumours. The editors and contributors, all prominent workers in the field, survey advances in the understanding of the relationship between the cancer cell and the immune response at the time of publication. Chapters review in depth the function of immune surveillance and mechanisms of tumour immunity, the role of T lymphocytes and oncogenes in the immune response to cancer, and the potential for immunotherapy of cancer. Areas of tumour immunology that were new at the time of this book's publication are presented, including progress in the development of tumour vaccines with particular reference to melanoma. The volumes in this series are intended for a wide audience of clinicians and researchers with an interest in the applications of biomedical science to the understanding and management of cancer.

    • Authoritative guide to revolutionary changes in the field
    • This is a key area: cell biology and treatment (particularly the search for cancer vaccines)
    • Editors and contributors are world-class clinical scientists

    Reviews & endorsements

    Review of the hardback: ' … will serve as a good text-book on cancer immunology and/or an excellent reference source on its individual topics. It can be recommended to clinicians, researchers and even undergraduates wishing to deepen their knowledge of this field.' Anton B. Alexandfoff, Immunology News

    Review of the hardback: ' … an excellent source of information which will be most helpful to the clinicians involved or interested in the various clinical vaccine trials that have been or will be implemented in the next five years.' J.-C. Cerottini, Annals of Oncology

    Review of the hardback: ' … there is much to commend the book. It will appeal mainly to clinicians and scientists who have some basic knowledge of cancer and immunology.' J. A. Ledermann, Journal of the Royal Society of Medicine

    Review of the hardback: ' … a balanced overview of the state-of-the-art, with special emphasis on the new potential for cancer immunotherapy … an excellent source of information'. Annals of Oncology

    See more reviews

    Product details

    November 2010
    Paperback
    9780521159470
    374 pages
    229 × 152 × 21 mm
    0.55kg
    Available

    Table of Contents

    • Contributors
    • Series Editor's Preface
    • Abbreviations
    • 1. Introduction and historical perspectives Michael Browning and A. G. Dalgleish
    • 2. The immunosurveillance of cancer: specific and non-specific mechanisms Richard G. Vile, Heung Chong and Sina Dorudi
    • 3. Antigen processing and presentation Nicholas C. Testifo and Michael Wang
    • 4. The role of the MHC class I in tumor immunity Michael Browning
    • 5. Human tumor antigens recognized by Cytolytic T Lymphocytes Pierre G Coulie
    • 6. Peptide-specific CTL directed against viral oncogene products Mariet C.W. Feltkamp, Cornelis J. M. Melief and W. Martin Kast
    • 7. Cellular oncogenes for tumor immunity: immunotherapy Hans J. Strauss and A. Maria Dahl
    • 8. Co-stimulatory molecules and their role in tumour immunity A. G. Dalgleish
    • 9. The role of cytokines in tumour rejection Guido Forni and Robin Foa
    • 10. Inhibition of nonhemopoietic cancer cell growth by Interleukin-4 and related cytokines Dave S. B. Hoon, Takashi Morisaki and Richard Essner
    • 11. Current concepts concerning melanoma vaccines Donald L. Morton and Mepur H. Ravindranath
    • 12. Immune responses to mucins Rosalind A. Graham and Joyce Taylor-Papadimitriou
    • 13. Heat shock protein-peptide complexes: pan-valent vaccines against cancers and infectious diseases Ryuichiro Suto and Pramod K. Srivastave
    • 14. The potential of gene transfer to alter the immune response to tumors Bernard A. Fox and Gary J. Nabel
    • 15. Applications of antibody gene technology Robert E. Hawkins and Kerry A. Chester
    • Index.
      Contributors
    • Michael Browning, A. G. Dalgleish, Richard G. Vile, Heung Chong, Sina Dorudi, Nicholas C. Testifo, Michael Wang, Pierre G Coulie, Mariet C.W. Feltkamp, Cornelis J. M. Melief, W. Martin Kast, Hans J. Strauss, A. Maria Dahl, Guido Forni, Robin Foa, Dave S. B. Hoon, Takashi Morisaki, Richard Essner, Donald L. Morton, Mepur H. Ravindranath, Rosalind A. Graham, Joyce Taylor-Papadimitriou, Ryuichiro Suto, Pramod K. Srivastave, Bernard A. Fox, Gary J. Nabel, Robert E. Hawkins, Kerry A. Chester

    • Editors
    • A. G. Dalgleish , St George's Hospital Medical School, University of London
    • M. J. Browning , University of Leicester
    • Karol Sikora