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Diabetes

Diabetes

Diabetes

Clinical Science in Practice
R. D. G. Leslie, St Bartholomew's Hospital, London
David C. Robbins
March 1995
Hardback
9780521450294
£177.00
GBP
Hardback

    This significant new publication provides a summary and overview of the most recent scientific advances in diabetes research, and highlights the role of these developments in advancing clinical practice. Diabetes is one of the major causes of morbidity and mortality in the developed world, and its prevalence elsewhere is on the increase. It affects in excess of 100 million people worldwide. Recent scientific advances have clarified our understanding of the causes and consequences of this devastating disease. These scientific developments are playing an increasingly important role in clinical practice and could well lead the way to the prevention of complications and even a cure for the disease. An international and authoritative team of authors draws together this knowledge and the most recent developments to provide an up-to-date account which will benefit researchers and clinicians.

    • International and authoritative
    • Comprehesive and up to date coverage
    • Important and relevant to clinical practice

    Reviews & endorsements

    'The editors, together with the eminent contributors, combine to make this an outstandingly informative book … each specialist topic can stand alone as a review of the most recent research … For anybody interested in diabetes it is an essential read.' D. M. Gasparro, British Journal of Biomedical Science

    'In Diabetes: Clinical Science in Practice distinguished scientists provide an authoritative analysis of their subjects and assess the implications of recent advances.' Michael Edmonds, British Medical Journal

    'The book is as up to date as a multiauthor textbook can hope to be … It should fulfil the editors' intentions of increasing the scientific understanding of diabetes in their readers, in the hope of improving the care of diabetic patients.' Michael Edmonds, British Medical Journal

    ' … as up to date as a multiauthor textbook can hope to be, containing many references to studies published in 1993 and 1994.' Michael Edmonds, British Medical Journal

    See more reviews

    Product details

    March 1995
    Hardback
    9780521450294
    508 pages
    257 × 195 × 28 mm
    1.191kg
    102 b/w illus. 38 tables
    Out of stock in print form with no current plan to reprint

    Table of Contents

    • 1. The regulation of insulin gene transcription
    • 2. Molecular structure of insulin
    • 3. Regulation of insulin secretion
    • 4. Insulin receptors
    • 5. The role of protein phosphorylation in insulin action
    • 6. Glucose transport mechanisms
    • 7. Glucose homeostasis
    • 8. Epidemiology of insulin-dependent diabetes mellitus (IDDM)
    • 9. Genetics of IDDM
    • 10. Aetiology of Type 1 (insulin-dependent) diabetes
    • 11. Epidemiology of NIDDM
    • 12. Genetic basis of the aetiology of non-insulin-dependent diabetes (NIDD)
    • 13. Islet amyloid polypeptide and amyloid in the islets of Langerhans
    • 14. Primary insulin resistance
    • 15. Epidemiology of the complications of diabetes
    • 16. Macrovascular disease in diabetes
    • 17. Diabetic neuropathy
    • 18. Diabetic foot infections
    • 19. Ocular complications of diabetes
    • 20. Diabetic nephropathy
    • 21. The personal, social and economic burden of diabetic complications
    • 22. Mortality among persons with diabetes
    • 23. Glycation and diabetic complications
    • 24. The sorbitol pathway and diabetic complications
    • 25. Proteinuria and diabetic complications
    • 26. Pharmacologic approaches to NIDDM
    • 27. Insulin and insulin analogues
    • 28. Hypoglycaemia
    • 29. Strategies for prevention of Type 1 (insulin-dependent) diabetes
    • 30. Treatment of early diabetic renal disease
    • 31. Pancreatic transplantation in humans with diabetes mellitus
    • 32. Rational insulin management of IDDM
    • 33. Rationale in the management of non-insulin-dependent diabetes mellitus (NIDDM)
    • 34. Psychosocial aspects of diabetes care
    • Index.
      Contributors
    • K. Docherty, A. R. Clark, H. S. Tager, S. L. Howell, J. F. Bak, O. Pedersen, D. E. Misek, A. R. Saltiel, M. N. Rosholt, P. A. King, P. C. Butler, A. Green, A. Lucassen, J. Bell, R. D. G. Leslie, E. A. M. Gale, W. H. Herman, L. S. Geiss, K. Osei, P. Westermark, E. Ferrannini, M. P. Stern, A. I. Vinik, B. D. Mitchell, S. B. Leichter, A. L. Wagner, J. T. O'Brian, L.-P. George, T. J. Lyons, B. Gonen, D. Dvornik, T. Deckert, A. Kofoed-Enevoldsen, P. M. Hansen, B. Myrup, R. C. Eastman, R. H. Jones, P. Pozzilli, C. E. Mogensen, D. M. Kendall, A. U. Teuscher, R. P. Robertson, R. E. Ratner, H. E. Lebovitz, M. Peyrot, Richard R. Rubin.