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Microbe-vector Interactions in Vector-borne Diseases

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Microbe-vector Interactions in Vector-borne Diseases

Microbe-vector Interactions in Vector-borne Diseases

S. H. Gillespie, University College London
G. L. Smith, Imperial College of Science, Technology and Medicine, London
A. Osbourn
May 2004
Available
Hardback
9780521843126
£70.99
GBP
Hardback
USD
eBook
    Description

    Several billion people are at daily risk of life threatening vector-borne diseases such as malaria, trypanosomiasis and dengue. This volume describes the way in which the causal pathogens of such diseases interact with the vectors that transmit them. It details the elegant biological adaptations that have enabled pathogens to live with their vectors and, in some circumstances, to control them. This knowledge has led to novel preventative strategies in the form of antibiotics and new vaccines which are targeted not at the pathogen itself but at its specific vector.

    • Details the elegant biological adaptations that have enabled pathogens to live with their vectors and in some circumstances control them
    • Written by international researchers in the field
    • Essential reading for researchers and clinicians working with these diseases

    Reviews & endorsements

    'The authors describe the advantages of insects as vectors and their numerous barriers to infection, including physico-chemical barriers, the gut, haemolymph, and the salivary glands themselves.' ASM News

    See more reviews

    Product details

    May 2004
    Hardback
    9780521843126
    396 pages
    236 × 158 × 24 mm
    0.762kg
    35 b/w illus. 10 colour illus. 14 tables
    Available

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    Contents

    Table of Contents

    • Preface
    • 1. Vector-borne diseases B. W. J. Mahy
    • 2. Evolution of tick-borne disease systems S. E. Randolph
    • 3. Insect transmission of viruses S. Blanc
    • 4. Interactive silencing of host gene expression S. W. Ding
    • 5. Reducing the prevalence of Borrelia in ticks A. G. Barbour
    • 6. Bunyavirus/mosquito interactions R. M. Elliott
    • 7. How do mosquito vectors live with their viruses? S. Higgs 8. Induction of vector competence S. Weaver
    • 9. Environmental influences on arbovirus infections and vectors P. S. Mellor
    • 10. Vector immunity N. A. Ratcliffe and M. M. A. Whitten
    • 11. Transmission of plant viruses by nematodes S. MacFarlane and D. J. Robinson
    • 12. Wolbachia host-symbiont interactions M. J. Taylor
    • 13. Pathogenic strategies of Anaplasma phagocytophilum, a unique bacterium that colonizes neutrophils J. A. Carlyon and E. Fikrig
    • 14. Interactions of Yersinia pestis with its flea vector that lead to the transmission of plague B. J. Hinnebusch
    • 15. Transgenic malaria P. W. Atkinson
    • 16. Vaccines targeting vectors G. A. T. Targett
    • Index.
      • Show more
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    Additional Information
    About the authors
      Contributors

    • B. W. J. Mahy, S. E. Randolph, S. Blanc, S. W. Ding, A. G. Barbour, R. M. Elliott, S. Higgs, S. Weaver, P. S. Mellor, N. A. Ratcliffe, M. M. A. Whitten, S. MacFarlane, D. J. Robinson, M. J. Taylor, J. A. Carlyon, E. Fikrig, B. J. Hinnebusch, P. W. Atkinson, G. A. T. Targett

      • Editors
    • S. H. Gillespie , University College London

      Stephen H. Gillespie is Professor of Medical Microbiology in the Department of Infectious Diseases at University College London, UK.

    • G. L. Smith , Imperial College of Science, Technology and Medicine, London

      Geoffrey L. Smith is a Wellcome Trust Principal Research Fellow and Head of Department of Virology at Imperial College London, UK.

    • A. Osbourn

      Anne Osbourn is a Group leader in the Sainsbury Laboratory, John Innes Centre, Norwich,UK.

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