Continuous Biopharmaceutical Processes
Continuous Biopharmaceutical Processes
Lucrèce Nicoud, Massachusetts Institute of Technology
Massimo Morbidelli, Eidgenössische Technische Hochschule Zürich
£125.00
GBPThis innovative reference provides a coherent and critical view on the potential benefits of a transition from batch to continuous processes in the biopharmaceutical industry, with the main focus on chromatography. It also covers the key topics of protein stability and protein conjugation, addressing the chemical reaction and purification aspects together with their integration. This book offers a fine balance between theoretical modelling and illustrative case studies, between fundamental concepts and applied examples from the academic and industrial literature. Scientists interested in the design of biopharmaceutical processes will find useful practical methodologies, in particular for single-column and multi-column chromatographic processes.
- Combines empirical and model-based approaches to design chromatographic processes
- Presents practical case studies from both the academic and industrial literature
- Clear and synthetic methodologies are provided and summarized in straightforward text
Product details
October 2018Hardback
9781108420228
346 pages
252 × 178 × 22 mm
0.81kg
142 b/w illus. 11 colour illus. 29 tables
Available
Table of Contents
- Preface
- 1. Introduction to biopharmaceutical processes
- 2. Fundamentals of protein chromatography
- 3. Counter-current separation processes
- 4. Counter-current chromatography for the capture step
- 5. Counter-current chromatography for the polishing steps
- 6. Protein conjugation
- 7. Protein aggregation in biopharmaceutical processes
- 8. Conclusion
- References
- Notation
- Index.
