Bound Carbohydrates in Nature
Bound Carbohydrates in Nature
Leonard Warren, The Wistar Institute of Anatomy and Biology, Philadelphia
April 1994
Paperback
9780521447430
Bound carbohydrates are an important and fascinating topic in biochemical and cancer research. Based on a series of invited lectures, this book focuses on the special role that bound carbohydrates play in nature and reflect the author's distinguished career in biochemical research. Some other topics covered are the properties of membrane glycoproteins, involved in the resistance of cells to drugs, and the metabolism of sugars and sialic acids, both of which form a pivotal role in the author's studies. The book chronicles just some of the huge advances that have been made in biochemistry over the past few decades.
Product details
April 1994Paperback
9780521447430
128 pages
215 × 139 × 8 mm
0.173kg
30 b/w illus. 7 tables
Available
Table of Contents
- 1. Introduction, history, microheterogeneity of bound carbohydrates
- function of bound carbohydrates
- inducible changes in bound carbohydrates
- programmed changes in bound carbohydrates
- a possible role for bound carbohydrates
- 2. Sialic acids
- distribution of sialic acids in nature
- the metabolism of hexamines and sialic acids
- metabolic control of hexosamines and sialic acids
- asparagine N-glycosylation
- processing of lysomal enzymes
- biosynthesis of O-linked oligosaccarides
- modification of sialic acids
- sialidases
- genetic metabolic disorders involving sialic acids, glycosidases, bound carbohydrates in malignancy
- 3. Multidrug resistance, properties of P-glycoprotein
- lysomes and multidrug resistance
- kinetics of influx and efflux of drugs, modulation of multidrug resistance
- the role of lipids in the accumulation of drugs by MDR cells
- P-170 and membrane lipids
- Overview.
